Name:
  • Hydrocortisone

Other Names:
  • Solu-Cortef

Classification:
  • Corticosteroid

Mechanism of Action:

  • Inhibits many of the substances that cause inflammation (cytokines, interleukin, interferon)
  • Inhibits the synthesis of pro-inflammatory enzymes
  • Considered a short-acting steroid

Indications:
  • Severe anaphylaxis
  • Asthma
  • COPD
  • Urticaria

Contraindications:
  • Untreated serious infections
  • Hypersensitivity

Dose:
  • 40 to 500 mg IV (rare to see prehospital, dose usually ordered by physician)
Routes:
  • IV
References:
  • Compendium of Pharmaceuticals and Specialties (CPS)
  • Pharmacology for the Prehospital Professional 2nd Edition

Last modified: Monday, 17 March 2025, 11:59 AM