Name:
  • Levodopa
Other Names:
  • L-Dopa

Classification:
  • Antiparkinson

Mechanism of Action:

  • Crosses the protective blood-brain-barrier, whereas dopamine itself cannot
  • Converts to Dopamine as it enters the CNS by the enzyme aromatic L-amino acid decarboxylase
  • Also converted into dopamine from within the PNS, resulting hyperdopaminergia causes many of the adverse side effects seen with sole L-DOPA administration

Indications:
  • Parkinson’s Disease
References:
  • Compendium of Pharmaceuticals and Specialties (CPS)

Modifié le: mercredi, 26 mars 2025, 13:43