Name:
  • Pantoprazole
Other Names:
  • Pantoloc

Classification:
  • Proton pump inhibitor

Mechanism of Action:

  • Binds irreversibly to H+K+ATPase (proton pumps) and suppresses the secretion of acid
  • Since it binds irreversibly to the pumps, new pumps have to be made before acid production could be resumed

Indications:
  • Treatment of conditions where a rapid reduction of gastric acid secretion is such as reflux esophagitis in patients who cannot tolerate oral medications or in patients with severe GI bleeding
References:
  • Compendium of Pharmaceuticals and Specialties (CPS)
  • Pharmacology for the Prehospital Provider 2nd Edition  

Last modified: Wednesday, 26 March 2025, 4:38 PM