Name:
  • Propofol 
Other Names:
  • Diprovan

Classification:
  • Beta-adrenergic receptor blocking agent

Mechanism of Action:

  • Inhibits GABA activity in the brain

Indications:
  • Induction and maintenance of sedation

Contraindications:
  • Hypersensitivity (including egg and soybean allergies)

Precautions:
  • Monitor EKG, BP, pulse oximetry
  • Use cautiously in elderly as clearance time may be increased and potentially cause severe hypotension

Adverse Effects:
  • Pain on induction
  • Hypotension
  • Apnea
  • Headache
  • Nausea and Vomiting

Dose:

  

Adult:
  • 25 – 75 mcg/kg IV as needed

Pediatric:
  • 1.0 mg/kg IV
Routes:
  • IV
References:
  • Compendium of Pharmaceuticals and Specialties (CPS)
  • Pharmacology for the Prehospital Provider 2nd Edition  

Modifié le: mercredi 26 mars 2025, 17:04